(English version below)
Auch im kommenden Sommersemester wird wieder eine Ringvorlesung mit spannenden Beiträgen von Professor*innen der Abteilung angeboten. Teilnehmen können alle (professoralen und promovierenden) Mitglieder sowie Angehörige der Abteilung. Wichtig: wir benötigen eine Anmeldung zur Ringvorlesung (einmalig per Mail an die Koordination für das gesamte Semester)!
Wir freuen uns auf eine rege Teilnahme, sowohl von Promovierenden als auch gerne von Professor*innen!
Termine jeweils mittwochs, 10:00-11:30 Uhr, online.
05. Juni 2024
Prof. Dr. Nilima Prakash, HS Hamm-Lippstadt
Stem cells, genome editing and neuropsychiatric disorders
The stem cell and genome editing fields in biomedicine have gained an incredible momentum with the recent approval of genome editing therapies and ongoing clinical trials of stem cell-based therapies for a variety of inherited and degenerative human diseases. Pluri- and multipotent stem cells of different origins and especially their cell derivatives with a particular tissue identity can be used for the replacement of lost cells. Examples for such applications are degenerative disorders such as Parkinson’s and Alzheimer’s Disease, age-related macula degeneration, and diabetes type I. Stem cells and their derivatives, however, are also used for the study of basic developmental processes in the otherwise inaccessible human embryo and fetus, the modeling of human diseases, and for drug and toxicity testing in an in vitro setting. In combination with nuclease-based genome editing, in particular CRISPR/Cas, stem cells are now applied for the cure of serious illnesses such as sickle cell anemia, beta-thalassemia, retinopathies and cancers. In this lecture, I will provide an overview of these themes on the background of our own research into dopamine-associated disorders, such as Parkinson’s Disease.
______________________________________________________________________________
In the upcoming summer semester, we will once again offer a lecture series featuring exciting contributions from professors of the department. All members (professors and doctoral candidates) as well as associates of the department are welcome to participate. Important: Registration for the lecture series is required (one-time registration via email to the coordination office for the entire semester)!
For English speaking participants: each contribution will have either the slides or the presentation in English.
We look forward to active participation, both from doctoral candidates and also from professors!
All dates: Wednesdays, 10:00-11:30 am, online
June 05, 2024
Prof. Dr. Nilima Prakash, HS Hamm-Lippstadt
Stem cells, genome editing and neuropsychiatric disorders
The stem cell and genome editing fields in biomedicine have gained an incredible momentum with the recent approval of genome editing therapies and ongoing clinical trials of stem cell-based therapies for a variety of inherited and degenerative human diseases. Pluri- and multipotent stem cells of different origins and especially their cell derivatives with a particular tissue identity can be used for the replacement of lost cells. Examples for such applications are degenerative disorders such as Parkinson’s and Alzheimer’s Disease, age-related macula degeneration, and diabetes type I. Stem cells and their derivatives, however, are also used for the study of basic developmental processes in the otherwise inaccessible human embryo and fetus, the modeling of human diseases, and for drug and toxicity testing in an in vitro setting. In combination with nuclease-based genome editing, in particular CRISPR/Cas, stem cells are now applied for the cure of serious illnesses such as sickle cell anemia, beta-thalassemia, retinopathies and cancers. In this lecture, I will provide an overview of these themes on the background of our own research into dopamine-associated disorders, such as Parkinson’s Disease.
